Facial hyperpigmentation: Any link to cancer?

  • Tina Deihim Internal Medicine Department, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
  • Nasim KhajaviRad Internal Medicine Department, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
  • Mahsa Abaszadeh Internal Medicine Department, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
  • Sahar Karimpour Reihan Internal Medicine Department, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. https://orcid.org/0000-0003-2669-6942
Keywords: Case reports, Cushing Syndrome, Hyperpigmentation, Paraneoplastic endocrine syndromes

Abstract

Introduction: Ectopic adrenocorticotropic hormone (ACTH) syndrome is recognized by edema, proximal muscle weakness, hypertension, diabetes and skin hyperpigmentation. This syndrome is mainly associated with malignancies. Case presentation: A 43-year-old woman came to our hospital with a history of new-onset diabetes, hypertension, edema and facial hyperpigmentation from four months before. Upon admission, she had alkalosis, hypokalemia, mild hypertension and low-grade fever. Due to abdominal pain, an abdominal ultrasound was performed, which revealed common bile duct (CBD) and pancreatic duct dilation. The abdominopelvic computed tomography (CT) scan showed a poorly-enhancing mass in the periampullary region. Conclusion: The patient's facial hyperpigmentation and hypokalemia appear to have been due to ACTH ectopic syndrome as a result of periampullary cancer.

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References

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Published
2018-08-26
How to Cite
Deihim, T., KhajaviRad, N., Abaszadeh, M., & Karimpour Reihan, S. (2018). Facial hyperpigmentation: Any link to cancer?. Advanced Journal of Emergency Medicine, 3(1), e9. https://doi.org/10.22114/ajem.v0i0.98
Section
Case (report / study)