Clinical Characteristics of Fatal Cases of COVID-19 in Tabriz, Iran: An Analysis of 111 Patients

  • Masoud Nouri-Vaskeh ORCID Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  • Neda Khalili ORCID School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  • Akbar Sharifi ORCID Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  • Pouya Behnam ORCID Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  • Zahra Soroureddin ORCID Cardiovascular Division, Imam Hossein Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran
  • Erfan Ahmadi Ade ORCID Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  • Nastaran Khalili ORCID School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  • Nafiseh Fadavi Department of Pediatric Pulmonology, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Behzad Baradaran ORCID Mail Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Keywords:
Coronavirus Disease-2019, COVID-19, Death, Iran, Mortality, SARS-CoV-2

Abstract

Introduction: The rapid worldwide spread, in addition to the morbidity and mortality associated with the novel coronavirus disease 2019 (COVID-19), have raised concern throughout the world. Identifying the characteristics of patients who died of COVID-19 is essential to implement preventive measures. Objective: We aimed at investigating these characteristics among the Iranian population in Tabriz. Methods: In this case series, we analyzed clinical characteristics, laboratory parameters, and imaging findings of 111 patients with a reverse transcriptase-polymerase chain reaction (RT-PCR)-confirmed COVID-19 diagnosis who died during hospitalization. The studied patients had been admitted to the hospital between February 2020 and May 2020. Results: The median age of patients was 73 years (IQR, 62-82 years) and approximately 70% of them were male. The median oxygen saturation on admission was 88% (IQR, 80-92%) and dyspnea, cough, and fever were the most common presenting symptoms. Among comorbidities, diabetes, hypertension, and cardiovascular diseases were more frequently observed among patients who had a fatal outcome. While ground-glass opacity was the most commonly reported finding on chest computed tomography, 5% of the patients had no abnormal finding on imaging. Chloroquine was the most frequently used medication for treatment. Conclusion: Our results showed that the majority of COVID-19 deaths occurred in male elderly with decreased levels of oxygen saturation and elevated levels of lactate dehydrogenase and erythrocyte sedimentation rate on admission.

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Author Biography

Zahra Soroureddin, Cardiovascular Division, Imam Hossein Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran

MD

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Published
2020-08-04
How to Cite
1.
Nouri-Vaskeh M, Khalili N, Sharifi A, Behnam P, Soroureddin Z, Ahmadi Ade E, Khalili N, Fadavi N, Baradaran B. Clinical Characteristics of Fatal Cases of COVID-19 in Tabriz, Iran: An Analysis of 111 Patients. Adv J Emerg Med.
Section
Original article